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The Best Chicken Spaghetti Recipe

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3.8 from 31 reviews

This Best Chicken Spaghetti is a creamy, cheesy, and flavorful casserole made with tender chicken, angel hair pasta, cream of chicken soup, salsa, and a blend of Mexican cheeses. Baked to bubbly perfection, it’s an easy and comforting dish perfect for family dinners or potlucks.

  • Total Time: 45 minutes
  • Yield: 8 servings

Ingredients

Chicken Spaghetti Mixture

  • 8 ounces angel hair pasta (half of a 16-ounce box)
  • 2 cups chopped, cooked chicken
  • 2 (10.5 ounce) cans cream of chicken soup
  • 1 cup salsa
  • ½ cup sour cream
  • 1 tablespoon taco seasoning
  • 1 cup Mexican cheese blend, divided use

Topping

  • 1 cup Mexican cheese blend
  • Dried parsley (optional)

Instructions

  1. Preheat Oven and Prepare Baking Dish: Preheat your oven to 350°F (175°C). Spray a 9×13-inch baking dish with nonstick cooking spray to prevent sticking.
  2. Cook Pasta: Cook 8 ounces of angel hair pasta according to the package directions, then drain well once cooked.
  3. Combine Ingredients: Return the drained pasta to the pot. Add 2 cups of chopped cooked chicken, 2 cans of cream of chicken soup, 1 cup of salsa, ½ cup sour cream, 1 tablespoon taco seasoning, and 1 cup of Mexican cheese blend (use half the cheese here). Stir well to combine everything evenly.
  4. Transfer to Baking Dish: Pour the combined mixture into the prepared baking dish, spreading it out evenly.
  5. Add Cheese Topping: Sprinkle the remaining 1 cup of Mexican cheese blend evenly over the top of the casserole. Optionally, add a light sprinkling of dried parsley for garnish.
  6. Cover and Bake: Cover the baking dish with aluminum foil to keep moisture in and bake in the preheated oven for about 25 minutes, or until the casserole is hot and bubbly.
  7. Serve: Remove from the oven, let it cool slightly, then serve warm as a delicious and hearty main dish.

Notes

  • You can use rotisserie chicken or leftover cooked chicken for convenience.
  • Adjust the amount of salsa and taco seasoning based on your preferred spice level.
  • For a lighter option, you can substitute sour cream with Greek yogurt.
  • Angel hair pasta cooks quickly; be careful not to overcook to avoid mushiness in the casserole.
  • This dish reheats well and can be stored in the refrigerator for up to 3 days.
  • Author: ELLA
  • Prep Time: 10 minutes
  • Cook Time: 35 minutes
  • Category: Casserole
  • Method: Baking
  • Cuisine: American